From the bench to the bedside: Medulloblastoma subtypes, cholinergic neuron function in the nucleus accumbens, and mechanisms o

نویسنده

  • Jason S. Hauptman
چکیده

Article: Subtypes of Medulloblastoma have Distinct Developmental Origins. Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

From the bench to the bedside: Medulloblastoma subtypes, cholinergic neuron function in the nucleus accumbens, and mechanisms of chronic neuropathic pain

Surg Neurol Int. 2011 Feb 14;2:16. From the bench to the bedside: Medulloblastoma subtypes, cholinergic neuron function in the nucleus accumbens, and mechanisms of chronic neuropathic pain. Hauptman JS. Intellectual and Developmental Disabilities Center and Department of Neurosurgery, Geffen School of Medicine at UCLA, Los Angeles, CA, USA. PMID: 21427785 [PubMed in process] PMCID: PMC3050033 F...

متن کامل

Functional Interaction between the Shell Sub-Region of the Nucleus Accumbens and the Ventral Tegmental Area in Response to Morphine: an Electrophysiological Study

This study has examined the functional importance of nucleus accumbens (NAc)-ventral tegmental area (VTA) interactions. As it is known, this interaction is important in associative reward processes. Under urethane anesthesia, extracellular single unit recordings of the shell sub-region of the nucleus accumbens (NAcSh) neurons were employed to determine the functional contributions of the VTA to...

متن کامل

Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside

Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics...

متن کامل

Sex differences and role of gonadal hormones in development of tolerance to morphine analgesia and glutamate level in the nucleus accumbens of rats: A microdialysis study

Introduction: Sex differences are observed in the development of tolerance to antinociceptive effect of opioid drugs such as morphine, but the underlying mechanisms remain unclear. Critical role of glutamate in the development and maintenance of opioid tolerance has been reported by many investigators. There are also evidences about interaction between gonadal hormones and neuromodulatory sy...

متن کامل

Effect of morphine on apoptotic factors caspase-3, PARP and Bax/Bcl-2 ratio in nucleus accumbens in conditioned place preference model in rat

Introduction: Nucleus accumbens (NAc) plays a critical role in neuronal reward circuits that are responsible for motivated and goal-directed behaviors. Some data suggest that morphine induces apoptosis in neurons, while other evidences show that morphine could have beneficial effects against neuronal cell death. This study was designed to evaluate the effect of morphine on apoptosis in the N...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011